医学突破！有3个父母的宝宝诞生

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世界新闻网






“新科学家”杂志报导，美国科学家用“三人”（three person）生育科技孕育的第一个宝宝已诞生。


五个月大的哈山（Abrahim Hassan）有父亲和母亲的正常DNA，加上一名捐赠者的一点“遗传密码”（genetic code）。


美国医师为确保哈山的约旦籍母亲的一种遗传疾病不会遗传给他，采取空前步骤。


专家说，此举开启了医学的新时代，可帮助有罕见遗传性疾病的家庭。

The world's first baby has been born using a new "three person" fertility technique, New Scientist reveals.

he five-month-old boy has the usual DNA from his mum and dad, plus a tiny bit of genetic code from a donor.

US doctors took the unprecedented step to ensure the baby boy would be free of a genetic condition that his Jordanian mother carries in her genes.

Experts say the move heralds a new era in medicine and could help other families with rare genetic conditions.

But they warn that rigorous checks of this new and controversial technology, called mitochondrial donation, are needed.

It's not the first time scientists have created babies that have DNA from three people - that breakthrough began in the late 1990s - but it is an entirely new and significant method.

Three person babies

Mitochondria are tiny compartments inside nearly every cell of the body that convert food into usable energy.

Some women carry genetic defects in mitochondria and they can pass these on to their children. In the case of the Jordanian family, it was a disorder called Leigh Syndrome that would have proved fatal to any baby conceived.

Scientists have devised a number of ways to circumvent this problem.

The US team, who travelled to Mexico to carry out the procedure because there are no laws there that prohibit it, used a method that takes all the vital DNA from the mother's egg plus healthy mitochondria from a donor egg to create a healthy new egg that can be fertilised with the father's sperm.

Their technique uses a healthy donor egg to provide healthy mitochondria.

The result is a baby with 0.1% of their DNA from the donor (mitochondrial DNA) and all the genetic code for things like hair and eye colour from the mother and father.

Eggs from a mother with damaged mitochondria and a donor with healthy mitochondria are collected 2) The majority of the genetic material is removed from both eggs 3) The mother's genetic material is inserted into the donor egg, which can be fertilised by sperm.

The UK has already passed laws to allow the creation of babies from three people.